Deer somtimes run far with the 00 buckshot.I just shot a doe five times with 12 pellet remington express mag.2 3/4 and she just was still putting up a fight.40-50 yd I dont think would drop a coyote with #4 buck.But the remington hevi-shot has a coyoyte round out.Made just for that game.Hevi-shot is nasty sh?t.